Can I Take Tylenol Before Epidural Steroid Injection

epidural steroid injection (ESI) is a popular medical procedure that many people undergo to relieve pain. However, like any medical procedure, there are risks and side effects that should be considered before undergoing ESI. In this article, we will explore some of the risks associated with ESI and how you can minimize them.

What is Epidural Steroid Injection?

Epidural steroid injection is a type of anesthesia used during childbirth. Epidural steroid injection is given through a needle that goes into your back. The injection causes you to feel painless and sleepy. Epidural steroids are also used during other surgeries, including shoulder and neck surgery.

What are the Side Effects of Epidural Steroid Injection?

Epidural steroid injection may cause side effects such as fever, chills, headache, muscle aches and a general feeling of malaise. In rare cases, epidural steroid injection can cause a serious infection in the area where the injection was given. Epidural steroids can also worsen preexisting back pain conditions.

Is it Safe to Take Tylenol Before Epidural Steroid Injection?

Epidural steroid injections may cause dizziness and drowsiness, which can make it unsafe to drive or operate heavy machinery. Before the injection, it is important to discuss any medications you are taking with your doctor. Some common over-the-counter medications that can increase the risk of side effects from epidural steroids include ibuprofen and acetaminophen (Tylenol). If you are going to receive an epidural steroid injection, it is best to avoid taking any medications for at least two hours before the procedure. If you do take a medication before the injection, be sure to let your doctor know so that he or she can adjust the dosage accordingly.


Epidural steroid injections can be a bit scary, but they are absolutely necessary for some people. Before you get the injection, it is important to talk to your doctor about any medications or supplements that you’re taking and whether they could interact with the epidural steroid. In addition, it is also important to know that Tylenol (acetaminophen) can interfere with the effectiveness of epidural steroids, so please avoid taking this medication before your injection.