Kidney disease
                                 # 9. cause of death in 2005

The cause is unknown, but the disease may occur after:Allergic reactions, Recent immunizations, Viral infection
"In 2005, more than 485,000 people were living on dialysis or with a transplant, at a total cost of $32 billion. Medicare
pays for much of that, because it provides coverage for patients needing dialysis or transplant even if they are not yet
65. In fact, kidney disease and kidney failure account for more than a quarter of Medicare’s annual expenditures."

"according to Julie Ingelfinger, a Harvard Medical School professor and pediatric nephrologist," "pointed to  E. coli
specifically, noting that HUS (hemolytic-uremic syndrome) is a long-term consequence of  E. coli  that is known to cause
pediatric kidney failure.   “Research into the long-term effects of foodborne disease is increasingly important because it
is unquantified and goes on for decades,”

Patients with unremitting nephrotic syndrome should be considered for combined dietary and lipid-lowering drug
therapy. Urinary losses of binding proteins lead to the observed abnormalities in the endocrine system and in trace
metals, and urinary losses of coagulation factors contribute to the
hypercoagulable state (thick blood).

Below are links to a few disease causing microorganisms studies show cause Kidney disease as well as
Inorganic Chemical Contaminants, Synthetic Organic Contaminants,  including pesticides & herbicides and
Volatile Organic Contaminants

EPA  did not include these pollutants as causing disease in the
Part 503 sludge biosolids risk assessment

Kidney infection (pyelonephritis) is a specific type of urinary tract infection (UTI) that generally begins in your urethra or
bladder and travels up into your kidneys. If not treated properly, kidney infection can permanently damage your
kidneys or spread to your
bloodstream and cause a life-threatening infection. Prompt medical attention is required.

Bacteria from an infection elsewhere in your body also can spread through your bloodstream to your kidneys. Kidney
infection is unusual through this route, but it can occur in some circumstances — for instance, when a foreign body,
such as an artificial joint or
heart valve, gets infected. Rarely, kidney infection results after kidney surgery
http://www.mayoclinic.com/health/kidney-infection/DS00593

Inorganic Chemical Contaminants


Cadmium
Short-term: EPA has found cadmium to potentially cause the following health effects when people are exposed  to it at
levels above the MCL for relatively short periods of time: nausea, vomiting, diarrhea, muscle cramps,  salivation,
sensory disturbances, liver injury, convulsions, shock and renal failure.  
Long-term: Cadmium has the potential to cause the following effects from a lifetime exposure at levels above the  MCL:
kidney, liver, bone and blood damage

Chromium
Long-term: Chromium has the potential to cause the following effects from a lifetime exposure at levels above
the MCL: damage to liver, kidney circulatory and nerve tissues; skin irritation

Chromium
Use of water that exceeds the Action Level over many years could cause liver or kidney damage. People with Wilsons
disease may be more sensitive than others to the effect of copper contamination and should consult their health care
provide

Lead
Long-term effects: Lead has the potential to cause the following effects from a lifetime exposure at levels above
the MCL: stroke and kidney disease; cancer.

Mercury
Short- or Long-term: EPA has found mercury to potentially cause the following health effects when people are
exposed to it at levels above the MCL for relatively short periods of time: kidney damage.

Nitrate and Nitrite
Short-term: Excessive levels of nitrate in drinking water have caused serious illness and sometimes death. The
serious illness in infants is due to the conversion of nitrate to nitrite by the body, which can interfere with the
oxygen-carrying capacity of the childs blood. This can be an acute condition in which health deteriorates rapidly
over a period of days. Symptoms include shortness of breath and blueness of the skin.

Long-term: Nitrates and nitrites have the potential to cause the following effects from a lifetime exposure at
levels above the MCL: diuresis, increased starchy deposits and hemorrhaging of the spleen.

Selenium
EPA has found selenium to potentially cause the following health effects when people are exposed to it at levels above
the MCL for relatively short periods of time:
Long-term: Selenium has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: hair and fingernail loss; damage to kidney and liver tissue, and the nervous and circulatory systems

Thallium
Long-term: Thallium has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: changes in blood chemistry; damage to liver, kidney, intestinal and testicular tissues; hair loss.


Synthetic Organic Contaminants,  including pesticides & herbicides


2,4-D
Long-term: 2,4-D has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to the nervous system, kidneys and liver.

2,4,5-TP (Silvex)
Short-term: EPA has found 2,4,5-TP to potentially cause the following health effects when people are exposed to it
at levels above the MCL for relatively short periods of time: depression and other nervous system effects,
weakness, stomach irritation and minor damage to liver and kidneys.
Long-term: 2,4,5-TP has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: minor liver and kidney damage.

Alachlor
Long-term: Alachlor has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: damage to liver, kidney, spleen; lining of nose and eyelids; cancer.

Atrazine  
Short-term: EPA has found atrazine to potentially cause the following health effects when people are exposed to it
at levels above the MCL for relatively short periods of time: congestion of heart, lungs and kidneys; low blood
pressure; muscle spasms; weight loss; damage to adrenal glands.

Chlordane
Long-term: Chlordane has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: damage to liver, kidneys, heart, lungs, spleen and adrenal glands; cancer.

Dibromochloropropane
Short-term: EPA has found DBCP to potentially cause the following health effects when people are exposed to it at
levels above the MCL for relatively short periods of time: kidney and liver damage and atrophy of the testes.
Long-term: DBCP has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
kidney damage and antifertility; cancer.

Epichlorohydrin
EPA has found epichlorohydrin to potentially cause the following health effects when people are
exposed to it at levels above the MCL for relatively short periods of time: skin irritation; detrimental effects on liver,
kidneys, central nervous system.

Ethylene dibromide
Long-term: EDB has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to the respiratory system, nervous system, liver, heart, and kidneys; cancer.

Glyphosate
Long-term: Glyphosate has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: kidney damage, reproductive effects.


Hexachlorobenzene  
Long-term: HCB has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to liver and kidneys; reproductive effects; benign tumors of endocrine glands; cancer.

Hexachlorocyclopentadiene
Short-term: EPA has found HEX to potentially cause the following health effects when people are exposed to it at
levels above the MCL for relatively short periods of time: gastrointestinal distress; damage to liver, kidneys and
heart.
Long-term: HEX has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to the stomach and kidneys.

Lindane
Long-term: Lindane has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: liver and kidney damage.

Methoxychlor  
Short-term: EPA has found methoxychlor to potentially cause the following health effects when people are exposed
to it at levels above the MCL for relatively short periods of time: central nervous system depression, diarrhea, and
damage to liver, kidney and heart tissue.
Long-term: Methoxychlor has the potential to cause the following effects from a lifetime exposure at levels above
the MCL: damage to liver, kidney and heart tissue; retards growth.

Pentachlorophenol  
Long-term: Pentachlorophenol has the potential to cause the following effects from a lifetime exposure at levels
above the MCL: reproductive effects and damage to liver and kidneys; cancer.

Simazine
Long-term: Simazine has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: tremors; damage to testes, kidneys, liver and thyroid; gene mutations; cancer.

Toxaphene  
Long-term: Toxaphene has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: liver and kidney degeneration; central nervous system effects; possible immune system suppression; cancer.

Volatile Organic Contaminants


Carbon Tetrachloride
Short-term: EPA has found carbon tetrachloride to potentially cause the following health effects when people are
exposed to it at levels above the MCL for relatively short periods of time: liver, kidney and lung damage.

Chlorobenzene  
Short-term: EPA has found chlorobenzene to potentially cause the following health effects when people are exposed
to it at levels above the MCL for relatively short periods of time: anesthetic effects and impaired liver and kidney
function.
Long-term: Chlorobenzene has the potential to cause the following effects from a lifetime exposure at levels above
the MCL: liver, kidney and central nervous system damage.

o-Dichlorobenzene
Long-term: o-DCB has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to the nervous system, liver, kidneys and blood cells.

1,2-Dichloroethane
Short-term: EPA has found 1,2-dichloroethane to potentially cause the following health effects when people are
exposed to it at levels above the MCL for relatively short periods of time: central nervous system disorders, and
adverse lung, kidney, liver circulatory and gastrointestinal effects.

Ethylbenzene
Long-term: Ethylbenzene has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: damage to the liver, kidneys, central nervous system and eyes.

1,2,4-Trichlorobenzene
Short-term: EPA has found 1,2,4-trichlorobenzene to potentially cause the following health effects when people are
exposed to it at levels above the MCL for relatively short periods of time: changes in liver, kidneys and adrenal glands

1,1,2-Trichloroethane
Long-term: 1,1,2-TCE has the potential to cause the following effects from a lifetime exposure at levels above the
MCL: damage to liver and kidneys; cancer.

Toluene
Long-term: Toluene has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
more pronounced nervous disorders such as spasms, tremors, impairment of speech, hearing, vision, memory,
coordination; liver and kidney damage.

Xylenes  
Long-term: Xylenes has the potential to cause the following effects from a lifetime exposure at levels above the MCL:
damage to the central nervous system, liver and kidneys.

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