APMIS Volume 111 Issue 4 Page 474-476, April 2003
To cite this article: BILGIN ARDA, SOHRET AYDEMIR, TANSU YAMAZHAN, ABDULLAHI HASSAN, ALPER
TÜNGER, DEMIR SERTER (2003)
Comamonas testosteroni meningitis in a patient with recurrent cholesteatoma
BILGIN ARDA,11Department of Infectious Diseases and Clinical Microbiology, Ege University, Medical Faculty, Izmir,
and Bilgin Arda, Department of Infectious Diseases and Clinical Microbiology, Ege University, Medical Faculty, 35100
Comamonas testosteroni, a lesser-known member of the genus, has shown little apparent capacity for causing
infections in humans. We here present a case of purulent meningitis due to C. testosteroni, which occurred in a
patient who had recurrent cholesteatoma. Ceftriaxone treatment was not effective in this patient even though in vitro
the bacteria were susceptible to the drug. The patient responded well to meropenem therapy.
South Med J. 2003 Aug ;96 (8):815-7 14515927
Bacteremia due to Comamonas species possibly associated with exposure to tropical fish.
[My paper] Marcus D Smith , Jeremy D Gradon
Comamonas species are environmental gram-negative rods that grow forming pink-pigmented colonies. Despite their
common occurrence in nature, they rarely cause human infection. We present a case of Comamonas bacteremia that
we think may have been related to tropical fish exposure. The patient was treated successfully with levofloxacin.
Mesh-terms: Administration, Oral; Aged; Aged, 80 and over; Animals; Animals, Domestic, microbiology; Anti-Infective
Agents, therapeutic use; Bacteremia, diagnosis; Bacteremia, drug therapy; Bacteremia, transmission; Bacteremia,
veterinary; Causality; Comamonas; Diagnosis, Differential; Drug Resistance; Environmental Exposure, adverse
effects; Fever, microbiology; Fish Diseases, microbiology; Fish Diseases, transmission; Gram-Negative Bacterial
Infections, diagnosis; Gram-Negative Bacterial Infections, drug therapy; Gram-Negative Bacterial Infections,
transmission; Gram-Negative Bacterial Infections, veterinary; Human; Male; Microbial Sensitivity Tests; Ofloxacin,
therapeutic use; Pharyngitis, microbiology; Tomography, X-Ray Computed; Treatment Outcome; Zoonoses,
microbiology; Zoonoses, transmission;
1983 Jun; 15 (2): 1715-9); Comamonas acidovorans causes endocarditis to medical addict (Horowitz H. et al. , J. Clin.
Microbiol. , 28,143-145, (1990) ); Corynebacterium diphtheriae causes respiratory diphtheria (Dobie RA, et al. , JAMA.
1979; 242: 2197-2201), myocarditis (Boyer NH, et al. , N Engl J Med. 1948 ; 239 : 913. ), paralysis of eyeball's
movement ciliary (Kallick CA, et. al., III Med J. 1970sol37 : 505- 512; and Naiditch MJ, et al. , Am J Med. 1954,, 17 :
229-245), functional disorder of face, pharynx, larynx, pleurisy peripheral nerve, skin diphtheria (Koopman JS, et al. , J