BMC Infect Dis. 2006 Dec 29;6 (1):179 17194310
Case report: Infective endocarditis caused by Brevundimonas vesicularis.
[My paper] Mei-Li Yang , Yen-Hsu Chen , Tun-Chieh Chen , Wei-Ru Lin , Chun-Yu Lin , Po-Liang Lu
ABSTRACT: BACKGROUND: There are few reports in the literature of invasive infection caused by Brevundimonas
vesicularis in patients without immunosuppression or other predisposing factors. The choice of antimicrobial therapy for
bacteremia caused by the pathogen requires more case experience to be determined. CASE PRESENTATION: The
case of a 40-year-old previously healthy man with subacute endocarditis proposed to be contributed from an occult
dental abscess is described. The infection was found to be caused by B. vesicularis on blood culture results. The
patient recovered without sequelae after treatment with ceftriaxone followed by subsequent ciprofloxacin therapy owing
to an allergic reaction to ceftriaxone and treatment failure with ampicillin/sulbactam. CONCLUSIONS: To our knowledge,
this is the first report of B. vesicularis as a cause of infective endocarditis. According to an overview of the literature
and our experience, we suggest that third-generation cephalosporins, piperacillin/tazobactam, and ciprofloxacin are
effective in treating invasive B. vesicularis infections, while the efficacy of ampicillin-sulbactam needs further evaluation.
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