| GENETIC DRUG RESISTANT FOOD POISONING DISASTER? By Jim Bynum 3-19-2007 (update July 2009) http://cfpub.epa.gov/ncer_abstracts/index.cfm/fuseaction/display.abstractDetail/abstract/8980/report/0 Food allergy, defined as an adverse immunological response to food, affects more than 11 million Americans and has doubled in incidence between 1997 and 2002. Severe anaphylaxis triggered by reactions to foods is responsible for 150 deaths and more than 30,000 emergency room visits in the United States per year. Despite this impact on health care expenditures, relatively little is known about the risk factors, disease pathogenesis, or the cellular and molecular processes involved in generating food allergy. Unlike other allergic diseases, such as asthma, eczema or rhinitis, food allergy has no current treatments or therapies and patients are left with the only options being strict food avoidance and injectable epinephrine for treatment of responses during accidental exposure. The incidence of food allergy is increasing at an alarming rate, and so research into pathogenesis and treatment is absolutely paramount. The literature supports a central role of the Th2-induced allergen-specific IgE in the pathogenesis of allergic disorders. However, mounting evidence supports the lack of correlation between specific IgE levels and incidence, severity or threshold of responsiveness in food allergy. These findings led us to question the role of allergen-specific IgG in the regulation of Th2 differentiation and the pathogenesis of allergic disorders. ------------------------------------------------------------------------------------------------------------------------------------------------- It appears that the EPA, USDA, FDA and CDC’s 1981 policy to promote the disposal of reclaimed sewage effluent toilet water and sewage biological solids in sludge on fruit, food crops, lawns, parks, and school yards was created to cover up the genetic engineering programs release of altered drug resistant bacteria and viruses into the environment. We should ask if this is crude attempt at population control. As the disease organisms became more deadly and spread through the environment infecting more people, EPA expanded the policy and it has become law in many states, which actually issue permits to put your health at risk. This health risk shows up in prescription drug sales. According to an NRDC published article in it's OnEarth magazine by Elizabeth Royte, "Prescription drug sales rose by an annual average of 11 percent between 2000 and 2005. Three hundred million Americans now fill more than three billion prescriptions a year;" This is an interesting situation since NRDC has signed several agreements over the years not to sue EPA over Clean Water Act violations concern sludge disposal on cropland. The prescriptions correlate with the increasing more deadly strains of bacteria. In a March 2007, Clostridium difficile– associated Disease in New Jersey Hospitals, 2000–2004, Esther T. Tan, et.al., reported, "During 2000–2004, participating hospitals reported a total of 13,394 CDAD cases. The mean annual rate of CDAD increased from 3.7/1,000 admissions in 2000 to 7.7/1,000 admissions in 2004, which represented a >2-fold increase in CDAD rates during the 5-year period" "In 2005, the Centers for Disease Control and Prevention (CDC) reported on a new, epidemic, toxin gene–variant strain of C. difficile on the basis of a study of isolates collected from hospitals in multiple states, including New Jersey." CDC report the new epidemic strain in 2005, Severe Clostridium difficile--Associated Disease in Populations Previously at Low Risk --- Four States, 2005 "C. difficile exotoxins A and B cause colonic dysfunction and cell death. The epidemic strain produces 16 times more toxin A and 23 times more toxin B compared with other common strains" "C. difficile-- associated disease (CDAD) ranges in severity from mild diarrhea to fulminant colitis and death." "In 2005, the Pennsylvania Department of Health (PADOH) and CDC received several case reports of serious CDAD in otherwise healthy patients with minimal or no exposure to a health-care setting." "This report summarizes the results of the investigation in Pennsylvania and three other states, which indicated the presence of severe CDAD in healthy persons living in the community and peripartum women, two populations previously thought to be at low risk." We can start to get an idea of how C. difficile picked up these new deadly toxins from a study on the self-replication DNA plasmids found in food and in the plague bacteria released in March 2007, Multiple Antimicrobial Resistance in Plague: An Emerging Public Health Risk, authors Timothy J. Welch, et.,al, expose the tip of this genetic engineering program iceberg EPA turned lose in 1980. Drug resistant plasmid markers are inserted into genetically engineered organisms and food crops. Press release But first lets look at what was known. This is not new information. In an 1982 EPA study, Effect of UV light disinfection on antibiotic-resistant coliforms in wastewater effluents, M. C. Meckes' noted, "In 1959, Wantanabe (31) discovered that some Escherichia coli strains could transfer antibiotic-senstive strains of shigella spp. Subsequent research has demonstrated that bacteria carrying transmissible R-factors [genetic transfer] are responsible for the spread of multiple antibiotic resistence among members of the Entero-bacteriaceae (such as E. coli, Samonella typi, and Shigella dysenteriae) Aeromonas and Yersinis species, Pseudomonas, and Vibro cholerae ," The 1988 EPA study on distribution and marketing of sludge compost, Occurrence of Pathogens in Distribution and Marketing Municipal Sludges, by William A. Yanko, County Sanitation Districts of Los Angeles County, documented the close connection between Salmonella and Yersinia in California. Yanko said, "The potential bacterial pathogens regularly detected were Salmonella and Yersinia. Salmonellae were detected at both facilities. Yersinia only occurred significantly at the static pile facility and were isolated in a pattern consistent with a seasonal occurrence." He added, "Yersinia enterocolitica occurred at very high densities in some samples." "The significance of Yersinia populations at the static pile facility was uncertain, but isolation patterns suggested a seasonal occurrence." The significance of Yersinia populations in sewage effluent and biological solids sludge is not uncertain any more. As Welch noted in the new study:
Rob Brezsny may have discovered the secret behind EPA's apparent madness in the words of the Anglican clergyman Thomas Malthus. Brezsny said, "In his famous "Essay on the Principle of Population as It Affects the Future Improvement of Society," Malthus proposed killing off underprivileged people. "Instead of recommending cleanliness to the poor," he wrote, "we should encourage contrary habits. In our towns we should make the streets narrower, crowd more people into houses, and court the return of the plague. In the country, we should build villages near stagnant pools, and encourage settlement in marshy and unwholesome situations. But above all, we should reprobate specific remedies for ravaging diseases; and those benevolent, but much mistaken men, who have thought they were doing a service to mankind by projecting schemes for the total extirpation of particular disorders." The term food poisoning covers a multitude of exposure pathways to multiple chemicals, disease causing organisms and their genetic toxins. Any chemical, disease causing organism or its genetic toxin known to cause gastroenteritis in a person through the food chain will be classified as food poisoning when it is isolated in an infected individual. The actual pathway (i.e., direct contact, or through air, water and food) of exposure to the chemical, disease causing organism or its genetic toxin may never be known for most outbreaks. Over the past thirty years, bacterial and virus food poisoning have become much more serious as bacteria and viruses exchanged genetic DNA and genes to produce much more deadly toxins and proteins as well as becoming drug resistant to many antibiotics. It appears that the U.S. type Shigella was the first bacteria to exchange DNA and genes with its more deadly Central American cousin in the late 60s or early 70s in California. By the mid 70s, the benign E. coli which was a normally part of our stomach bacteria picked up the DNA and gene to become the Shiga-like toxin-producing E. coli 0157: H7 that has the ability to destroy internal organs. No medical treatment is available. Treatment with antibiotics will cause the body to be flooded with toxins and send the patient into toxic shock. The prevailing scientific theory, at the moment, is that the use of antibiotics to prevent infections in cattle is the reason for drug resistant bacteria running rampant through the environment and causing so much food poisoning and uncounted deaths. While the theory is a good public relations ploy to blame farmers, there isn’t much science behind the theory, since cattle get infected just like people. That’s not to say antibiotic use could not be a part of the current drug resistant bacterial problem. Antibiotics have been used as a pesticide since the 50s and antibiotic residues are also going into sewage treatment plant where bacteria are used to break down waste. Scientists as well as EPA have known since the 50s that bacteria exchange DNA and genes in the treatment plant and spit out drug resistant bacteria in the sewage effluent water and are concentrated in the sewage biological solids in sludge. Some of you may remember the tongue-in-cheek slogan “An apple a day keeps the doctor away.” The implication was that apples were health food and as a part of a good diet, there would be no need for the doctor. As I said this was a tongue-in-cheek slogan, because apples, and other fruits, were treated with the “miracle drugs” to kill bacteria that infected apples. In 1980, the National Academy of Science reported on the problem of the drug resistant of plant bacteria on fruits that started in the 50s. According to, Patricia S. McManus, 2001, Department of Plant Pathology, University of Wisconsin, Madison, Streptomycin and oxtetracycline are still used today as a pesticide. The use of these Miracle drugs as a silver bullet quickly led to drug resistant bacteria and the destabilization of plant disease control in the orchards. However, that is not the worse part, Agrobacterium and Pseudomonas bacteria are plant and soil bacteria that have not only developed drug resistance, they are now opportunist human pathogens that generally show up in hospital settings. Agrobacterium is one of the bacteria used to get genetically modified human genes into plants. You might want to think about that before you take a potted plant to your sick friend in the hospital. Xanthomonas is another plant disease that has developed drug resistance and become an opportunist human pathogen. Not only that, but as early as 1967, it was reported that the drug resistant plant pathogen Erwinia species caused disease in humans. Eating meat might be safer, according to the book, Secret Agents: The Menace of Emerging Infections by Madeline Drexler, “a 1993 study found higher levels of multidrug-resistant bacteria in intestines of vegetarians than in meat eaters.” Currently, health authorities still recommend a lot of fruit in your diet. It is an accepted fact that the use of antibiotics in humans and cattle create drug resistant bacteria. However, there is a caveat, a USDA investigation in 1982 did not find 0157:H7 in any cattle in the United States. By 1990 about 4 percent of cattle were infected with Salmonella. Since EPA and USDA approved the disposal of disease contaminated sludge on farms and grazing land cattle infections have increased dramatically. It is a scientific documented fact that viral plasmids will transfer DNA and drug resistant genes between bacteria and loose DNA plasmids may also be picked by bacteria and be more infective than the virus. This transfer of DNA and drug resistant genes has been document in sewage treatment since the 50s. It appears that humans have infected the cattle. Now we can add genetically engineered disease organisms to the mixture. Modified viruses are used to carry recombined DNA as well as used in vaccines. This may be more of an art than a science as no one can predict the final outcome down the road. As an example, during the 50s monkey cells were used to make poliovirus vaccine. It wasn’t until about 1960 that scientists discovered the SV40 monkey virus contaminated the vaccine. Today the SV40 virus is found to be involve in brain and bone tumors, mesotheliomas, as well as non-Hodgkin's lymphoma. It is interesting to note that the West Nile Virus (WNV) has transformed itself into a polio-like virus. Dr. Richard L. Bruno said, “Nearly 1% percent of those infected with WNV have paralysis, almost the same percentage as in as those infected with polioviruses; up to 15 percent of those severely affected by West Nile virus die, where about 15 percent of all polio patients died due to severe brain stem encephalitis called "bulbar polio." Dr. Bruno said, “On September 20, 2002, "The Washington Post" reported that the West Nile virus is for the first time affecting younger and healthier and has caused at least six cases of "polio-like paralysis," in arms, legs and even breathing muscles, causing several individuals to be placed on respirators. “ Dr. Bruno leaves us with two questions:
Seems like the WNV has also picked up a deadly genetic toxin gene recently. Most cases of polio and WNV only cause a mild flu-like symptom in a person with a good immune system, but that not does mean its not still in your body. Take the herpesvirus for example, everyone understands that it is a sexually transmitted disease, there is no treatment and you have it for life, but few realize it may cause cancer of the central nervous system as well as other diseases including chickenpox. Hang on there jasper, if herpesvirus causes chicken pox, it must not be sexual transmitted, them little kids are not have sex, are they? Some 40, 50 or even 60 years later the herpes virus may remind you it is still there with a bad case of shingles. Viruses are like bad relatives, they live forever. As an example, scientists have cloned a papillomavirus from a 16th century mummy. That is another sexually transmitted disease, or is it? Twenty-five million female children and women are infected. Does everyone really believe all those young children are having sex? Some times scientist appear to lack common sense. Drug resistant genes are also inserted as markers in genetically engineered bacteria. Since there has been such a dramatic increase in drug resistant bacteria in the last 25 to 30 years, there is a common (scientific and public) theory that genetic engineers are responsible for a major portion of the increase. In fact, that theory may have some validity since a patent was assigned to Stanford University in 1980 for a process to insert genes into non-disease causing E. coli so as to create a bacteria never before seen in nature. Since that time E. coli has been the workhorse of genetic engineering. In 1989 EPA published a list of 25 pathogens (disease causing organisms) in the proposed sludge use guidelines. The document stated that with the exception of the polio virus, bacteria and viruses only caused gastroenteritis. The implication was that polio has been eradicated so there could not be a problem with this virus. It was interesting that E. coli was the only organism which EPA listed as having pathogenic strains. It is the general consensus that pathogens in sewage only cause problems in developing countries. However, scientific consensus tends to forget many of the most deadly bacteria and viruses out of the over 1,400 organisms known to cause serious diseases, Since 1989, there has been a boom in genetic engineering projects. EPA has even permitted the use a insecticidal protein toxin, (delta-endotoxin producing gene) into food crops. The delta-endotoxins is a product of the B. thuringiensis (Bt) bacteria. The theory is that under normal conditions it is safe to expose humans, other mammals and non-targeted insects to this pesticide. However, the delta-endotoxin protein producing gene is encoded in a Bt plasmid which is inserted into the food crops. A plasmid is a DNA molecule capable of replicating on its own similar to a virus or bacteria. There are a number of different toxins produced by Bt plasmids and these plasmids may be freely exchanged between Bt bacteria, which indicates they are available for other organisms to pick up. The Bt protein toxin dissolves in the stomach and attachés to the epithelial cells that line the stomach creating pores (openings) in the cell membranes. The epithelial cells then die. The Bt protein toxin may enter the blood stream and attack other epithelial cells in the body. While these Bt protein toxins are only suppose to attack certain insects, this sounds a lot like what happens to the brain in Alzheimer's disease and mad cow disease as well as the human gut in acid reflux disease. Recent published research indicates that unless there is bacteria in the gut, the Bt protein toxin doesn’t effect insects. Wisconsin graduate student Nichole Broderick found that introducing the protein toxins with Enterobacter or E. coli producing Bt toxin did kill the insects. If this is indeed the case, a small Pico virus could pick up the protein toxin containing plasmid in the stomach and take it right to the brain. What is especially interesting is that EPA has been working with the BioTech industry since that first patent was issued in 1980. EPA implied it had little or no information to go on. As you can see from the above information it is still in the same position. Was it a coincidence that EPA created a policy about the same time to spread bacteria and viruses on food crops so human health problems couldn’t be traced back to the BioTech industry? Is it a coincidence that EPA refuses to investigate any human harm from the biological solids sludge disposed of as a fertilizer. According to the US Department of State, (2003)
What Johnson told Congress: Science is at the point now where genes can be moved between unrelated species. In the case of PIPs, scientists alter plants to produce pesticidal substances from any source, for example, from another plant, a bacterium or virus, etc. [human genes into sunflowers and Human hepatitis B virus into tobacco]
What Johnson told Congress: “The Agency believes that regulated biotechnology products are safe, provided they are used according to the approved labeling.” “The Framework established an approach to regulating the products of this new technology based on the characteristics of the products and the specific use of the product, not the process used to create it.”
What Johnson told Congress: “For toxicology, an acute oral toxicity test of the pesticidal substances on laboratory animals is required. At times, it has not been possible to make enough of the substance for testing purposes in the plant itself so EPA has allowed the exact same protein to be produced by bacteria and used for the testing.” “Currently, for an allergenicity assessment, EPA requires digestibility test, tests for heat stability, and a comparison of the structure of the protein to the structures of known food allergens.
What Johnson told Congress: “The Agency has also established tolerance exemptions for pesticidal proteins from viruses that have been moved to plants like watermelon, cucumber, potato, and papaya. In 1998, EPA registered a PIP based on the potato leaf roll virus (PLRV) and a Bt protein. The Bt protein and the PLRV protein were combined to provide virus and insect protection.”
Lets see, Johnson said EPA does not actually test the protein toxin, they test something similar. That does not sound like sound science. That sound like ass/u/me. EPA has worked with other countries to adopted its early 80s sludge policy of spreading disease organisms on farmland as well as home lawns, parks and school grounds, based on the same sound science. That same sound science approved the genetically engineered Starlink corn for animal feed. Which was promptly marketed without qualification. This happened for two reasons: 1) animal feed does not bring a premium price and 2) most storage elevators don’t have the facilities to handle animal feed corn separate from regular corn used for human food. The same situation applies to animal feed grown on sludge, but EPA has done nothing to prevent crops grown on sludge from entering the human food chain. With the farmers and storage elevators it is a don't ask, don't tell policy. In fact, according to Johnson, all future genetically engineered crops will go straight into the human food chain. What is more interesting is that EPA is now registering new genetically engineered microorganisms as “new chemical substances” that under certain conditions would not pose any unreasonable risk to public health or the environment. Why would EPA classify bacteria and viruses as a new chemical substance? Is this more sound science? According to EPA’s sound science genetically engineered bacteria and viruses used in the pulp and paper industry, bioremediation, biosensors and agricultural applications don’t exchange DNA or plasmids like other organisms? What Johnson told Congress:
Internationally,
You have to admit that engineers, scientists and doctors are fairly intelligent people, but they tend to dispose of everything possible in the sewage system. Perhaps, they assume there are some fairly intelligent people operating the sewage treatment plants and those people are working under regulations to protect the public created by some fairly intelligent people. Since engineers, scientists and doctors know there are some really bad bugs going into the sewer pipe from industry, laboratories and sick people at home and in hospitals. Common sense indicates that those bad bugs and chemical are going to come out of sewage treatment plant in either the sewage effluent water or in the sewage biological solids sludge. According to Kenneth Landau, California Regional Water Quality Control Board "Pesticides, oil, grease and antibiotics are among the agents that can harm or kill the biological treatments in a sewer treatment plant, Landau said." When that happens, reclaimed sewage effluent water used for irrigating food crops will be seriously contaminated. Neither, EPA, USDA, FDA or CDC want to discuss their 1981 policy of using disease organism contaminated sewage sludge on fruit and vegetable crops. In fact current EPA documents state the 1981 policy was for biosolids, just a name change to cover up the sludge facts. EPA claimed its sludge disposal policy as a fertilizer was based on sound science. However, the basic study was not done on disease organisms, it claimed the toxic metals in sludge did not cause cancer, even though it had a documents saying otherwise, it said that EPA did not have the information to determine if sludge was safe or not, and EPA still claims it is going to study the problem at some future date. In fact, EPA does state in it sludge regulation that exposure to the chemicals, metals, and disease causing organisms could cause death, disease, cancer etc. Since 1986, food poisoning incidences have explode from 2 million to 76 million in 1999. No estimates have been published since then, but death estimates have dropped from 9,100 in 1987 to 5,000 in 1999. Major foodborne illness outbreaks are hitting fast and furious. Rivers, streams and surface water are contaminated with disease causing bacteria and viruses. Yet, EPA, CDC and FDA are focusing the investigation on cattle manure? But when we observe the big picture, a different picture emerges. Papillomavirus now infect 25 million female children and women. No one has any idea how many male children and men are infected even though CDC classified it as a sexually transmitted disease. Attention-Deficit/Hyperactivity Disorder (ADHD) among our children and adults has exploded and is now epidemic effecting 5-7-percent or more of our children -- and adults. The paramyxoviruses, which causes mumps and measles caused 745,000 deaths in 2001. Human Obesity is now epidemic. Autism is epidemic with 1 in 150 children effected. Acid refux disease is epidemic. Alzheimer's disease is epidemic. The we have the flesh eating bugs, Staph bug causes new (Necrotizing) pneumonia, Aspergillus Necrotizing pneumonia, Group A Strep Necrotizing pneumonia, E. Coli Necrotizing pneumonia, Yersinis pneumonia. Without immediate medical attention, life expectancy is from 72 hours to one week. You get the picture. There is a major problem. Bacteria and viruses invade every part of our body. While they may only cause flu-like symptoms at first, they could lead to a quick death or the effects may not show up until later in life. The super bugs are here. Plant and soil bacteria now infect humans. Human bacteria have been picking up deadly toxin producing genes at an amazing rate. Necrotizing fasciitis (flesh eating bacteria) was a very rare invasive infection in 1990. The primary disease organism involved was streptococcus, but Staphylococcus (CA-MRSA) soon took over the primary position. Enterococci is fighting for the lead now with other bacteria capable of causing necrotizing fasciitis, including Bacteroides, Clostridium, Peptostreptococcus, Enterobacteriaceae coliforms, Proteus, Pseudomonas, and Klebsiella. While these are only a few of the new super bugs, we don’t want to forget E. coli which picked up the Shigella gene for an extremely deadly Shiga-like Central American toxin about the time genetic engineers started playing with bacteria. Now it appears that the EPA, USDA, FDA and CDC’s sludge disposal policy was created to cover up the genetic engineering programs release of altered bacteria and viruses into the environment. Based on Pennsylvania's beneficial use sludge permits and Virginia's mandating sludge disposal on cropland, this may even be a crude government attempt at population control. Why else would EPA continue to use faulty scientific test to assure the quality of water? Why would EPA insist it is safer to put biological contaminated sludge on you lawn, parks and school yards than it is to put it in a permitted landfill? Why else would EPA promote the use of biological contaminated sewage effluent water (using a faulty test) on food crops, lawns, parks and school grounds and even in building cooling towers? Why else would EPA refuse to investigate any health complaint? |